Cook pasta according to package directions, reserving ½ cup pasta water.
Heat 1 tablespoon of olive oil in a medium skillet. Cook chicken until golden brown and cooked all the way through, about 8 minutes. Remove from pan.
Add remaining tablespoon of olive oil to the pan. Cook red onion for 8 minutes. Sprinkle with flour, paprika, salt and crushed red pepper and stir to combine. Add white wine and pasta water and cook for 2 minutes. Add yogurt, sour cream and Worcestershire sauce and cook for 2 minutes more. Toss with pasta, chicken and parsley and serve warm with fresh ground black pepper.